Atomistry » Gold » PDB 5jjo-7pvj » 7dat
Atomistry »
  Gold »
    PDB 5jjo-7pvj »
      7dat »

Gold in PDB 7dat: The Crystal Structure of Covid-19 Main Protease Treated By Af

Enzymatic activity of The Crystal Structure of Covid-19 Main Protease Treated By Af

All present enzymatic activity of The Crystal Structure of Covid-19 Main Protease Treated By Af:
3.4.19.12; 3.4.22.69;

Protein crystallography data

The structure of The Crystal Structure of Covid-19 Main Protease Treated By Af, PDB code: 7dat was solved by Z.S.He, B.He, P.Cao, H.D.Jiang, Y.Gong, X.Y.Gao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 31.45 / 2.75
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 114.279, 53.985, 44.678, 90, 101.85, 90
R / Rfree (%) 19.4 / 22.8

Gold Binding Sites:

The binding sites of Gold atom in the The Crystal Structure of Covid-19 Main Protease Treated By Af (pdb code 7dat). This binding sites where shown within 5.0 Angstroms radius around Gold atom.
In total 2 binding sites of Gold where determined in the The Crystal Structure of Covid-19 Main Protease Treated By Af, PDB code: 7dat:
Jump to Gold binding site number: 1; 2;

Gold binding site 1 out of 2 in 7dat

Go back to Gold Binding Sites List in 7dat
Gold binding site 1 out of 2 in the The Crystal Structure of Covid-19 Main Protease Treated By Af


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 1 of The Crystal Structure of Covid-19 Main Protease Treated By Af within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Au801

b:36.3
occ:0.33
SG A:CYS145 2.3 45.4 1.0
O A:HOH958 2.9 50.0 1.0
CB A:CYS145 3.4 41.4 1.0
N A:GLY143 3.8 64.9 1.0
N A:CYS145 4.1 35.5 1.0
CE1 A:HIS41 4.2 26.1 1.0
CA A:GLY143 4.3 63.6 1.0
CA A:CYS145 4.4 38.2 1.0
OD1 A:ASN142 4.5 75.9 1.0
C A:GLY143 4.7 54.9 1.0
N A:SER144 4.7 41.9 1.0
NE2 A:HIS41 4.8 30.6 1.0
C A:ASN142 4.8 71.5 1.0
CA A:ASN142 4.8 68.3 1.0
CG A:ASN142 5.0 77.2 1.0

Gold binding site 2 out of 2 in 7dat

Go back to Gold Binding Sites List in 7dat
Gold binding site 2 out of 2 in the The Crystal Structure of Covid-19 Main Protease Treated By Af


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 2 of The Crystal Structure of Covid-19 Main Protease Treated By Af within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Au802

b:35.8
occ:0.16
SG A:CYS156 2.3 44.0 1.0
O A:HOH966 2.8 33.9 1.0
NZ A:LYS102 3.1 48.5 1.0
CG A:LYS102 3.4 39.0 1.0
O A:TYR101 3.8 33.4 1.0
CB A:CYS156 3.8 35.3 1.0
CD A:LYS102 3.9 37.5 1.0
CE A:LYS102 4.0 46.9 1.0
C A:TYR101 4.1 32.3 1.0
N A:TYR101 4.1 31.3 1.0
O A:HOH916 4.2 24.9 1.0
O A:HOH1007 4.4 36.3 1.0
CA A:TYR101 4.5 31.7 1.0
CB A:LYS100 4.6 28.1 1.0
C A:LYS100 4.6 27.5 1.0
N A:LYS102 4.7 28.3 1.0
CB A:LYS102 4.7 29.2 1.0
CA A:CYS156 4.9 31.0 1.0

Reference:

Z.S.He, F.Ye, C.Y.Zhang, Z.Y.Du, W.C.Zhao, Y.C.Gao, F.P.Gao, Y.H.Dong, J.D.Fan, B.He, P.Cao, X.J.Gao, X.F.Gao, B.Sun, J.C.Zhao, H.D.Jiang, J.X.Qi, H.D.Jiang, W.J.Tan, Y.Gong, X.Y.Gao. Single Gold Compound Synergized Inhibition of Sars-Cov-2 Replication and Direct Suppression of Inflammatory Cytokines in Vitro/Vivo To Be Published.
Page generated: Mon Jul 7 01:41:02 2025

Last articles

I in 7R4G
I in 7R4F
I in 7QBF
I in 7R4D
I in 7R4C
I in 7R48
I in 7R47
I in 7R46
I in 7R45
I in 7QUR
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy