Gold in PDB 6fx9: The X-Ray Structure of the Ferritin Nanocage Containing Au and Pt, Obtained Upon Encapsulation of A Single Heterobimetallic Compound Within the Protein Cage (Synchrtron Data)

The structure of The X-Ray Structure of the Ferritin Nanocage Containing Au and Pt, Obtained Upon Encapsulation of A Single Heterobimetallic Compound Within the Protein Cage (Synchrtron Data), PDB code: 6fx9 was solved by A.Merlino, G.Ferraro, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	104.89 / 1.50
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	181.680, 181.680, 181.680, 90.00, 90.00, 90.00
R / Rfree (%)	15.2 / 18.3

The structure of The X-Ray Structure of the Ferritin Nanocage Containing Au and Pt, Obtained Upon Encapsulation of A Single Heterobimetallic Compound Within the Protein Cage (Synchrtron Data) also contains other interesting chemical elements:

Cadmium	(Cd)	13 atoms
Chlorine	(Cl)	3 atoms

The binding sites of Gold atom in the The X-Ray Structure of the Ferritin Nanocage Containing Au and Pt, Obtained Upon Encapsulation of A Single Heterobimetallic Compound Within the Protein Cage (Synchrtron Data) (pdb code 6fx9). This binding sites where shown within 5.0 Angstroms radius around Gold atom.
In total only one binding site of Gold was determined in the The X-Ray Structure of the Ferritin Nanocage Containing Au and Pt, Obtained Upon Encapsulation of A Single Heterobimetallic Compound Within the Protein Cage (Synchrtron Data), PDB code: 6fx9:

Gold binding site 1 out of 1 in the The X-Ray Structure of the Ferritin Nanocage Containing Au and Pt, Obtained Upon Encapsulation of A Single Heterobimetallic Compound Within the Protein Cage (Synchrtron Data)


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 1 of The X-Ray Structure of the Ferritin Nanocage Containing Au and Pt, Obtained Upon Encapsulation of A Single Heterobimetallic Compound Within the Protein Cage (Synchrtron Data) within 5.0Å range: probe atom residue distance (Å) B Occ A:Au218 b:22.5 occ:0.35 SG A:CYS126 2.3 23.5 1.0 CB A:CYS126 3.1 17.9 1.0 O A:ASP122 3.5 12.8 1.0 CA A:PRO123 3.7 13.5 1.0 CA A:SER118 3.7 18.4 1.0 C A:ASP122 3.7 11.4 1.0 O A:HOH435 3.8 42.5 1.0 N A:PRO123 3.8 12.6 1.0 O A:GLY117 3.9 15.9 1.0 N A:SER118 4.0 17.3 1.0 C A:GLY117 4.0 17.2 1.0 N A:ASP122 4.1 12.8 1.0 CB A:SER118 4.2 22.6 1.0 CB A:PRO123 4.4 14.8 1.0 CA A:CYS126 4.5 14.2 1.0 CA A:ASP122 4.6 12.3 1.0 N A:CYS126 4.6 14.3 1.0 CD A:PRO123 4.7 13.0 1.0 C A:PRO123 4.8 13.6 1.0 OG A:SER118 4.8 29.8 1.0 C A:ALA121 4.9 14.4 1.0 C A:SER118 4.9 17.7 1.0 O A:PRO123 5.0 14.4 1.0 CA A:ALA121 5.0 16.3 1.0 CA A:GLY117 5.0 16.6 1.0

G.Ferraro, G.Petruk, L.Maiore, F.Pane, A.Amoresano, M.A.Cinellu, D.M.Monti, A.Merlino. Caged Noble Metals: Encapsulation of A Cytotoxic Platinum(II)-Gold(I) Compound Within the Ferritin Nanocage. Int. J. Biol. Macromol. V. 115 1116 2018.
ISSN: ISSN 1879-0003
PubMed: 29709536
DOI: 10.1016/J.IJBIOMAC.2018.04.142