Gold in PDB 5z8s: Human Mitochondrial Ferritin Mutant - C102A/C130A/E27C/E61C/E62C

All present enzymatic activity of Human Mitochondrial Ferritin Mutant - C102A/C130A/E27C/E61C/E62C:
1.16.3.1;

The structure of Human Mitochondrial Ferritin Mutant - C102A/C130A/E27C/E61C/E62C, PDB code: 5z8s was solved by J.Zang, B.Zheng, G.Zhao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.92 / 1.97
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	182.736, 182.736, 182.736, 90.00, 90.00, 90.00
R / Rfree (%)	16.6 / 20

The binding sites of Gold atom in the Human Mitochondrial Ferritin Mutant - C102A/C130A/E27C/E61C/E62C (pdb code 5z8s). This binding sites where shown within 5.0 Angstroms radius around Gold atom.
In total 2 binding sites of Gold where determined in the Human Mitochondrial Ferritin Mutant - C102A/C130A/E27C/E61C/E62C, PDB code: 5z8s:
Jump to Gold binding site number: 1; 2;

Gold binding site 1 out of 2 in the Human Mitochondrial Ferritin Mutant - C102A/C130A/E27C/E61C/E62C


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 1 of Human Mitochondrial Ferritin Mutant - C102A/C130A/E27C/E61C/E62C within 5.0Å range: probe atom residue distance (Å) B Occ A:Au201 b:59.2 occ:1.00 SG A:CYS27 2.6 33.8 1.0 SG A:CYS62 2.9 30.1 1.0 CB A:CYS27 3.0 15.3 1.0 CA A:CYS27 3.2 12.7 1.0 CB A:CYS62 3.4 17.1 1.0 CA A:CYS62 3.7 19.3 1.0 O A:CYS27 3.8 16.7 1.0 O A:CYS62 3.8 18.2 1.0 C A:CYS27 4.0 16.1 1.0 C A:CYS62 4.2 18.4 1.0 CB A:ALA30 4.3 13.7 1.0 CB A:HIS65 4.3 24.2 1.0 CG1 A:VAL110 4.4 18.4 1.0 N A:CYS27 4.5 14.5 1.0 N A:CYS62 5.0 21.2 1.0

Gold binding site 2 out of 2 in the Human Mitochondrial Ferritin Mutant - C102A/C130A/E27C/E61C/E62C


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 2 of Human Mitochondrial Ferritin Mutant - C102A/C130A/E27C/E61C/E62C within 5.0Å range: probe atom residue distance (Å) B Occ A:Au202 b:0.4 occ:0.49 CB A:CYS61 2.4 33.6 1.0 SG A:CYS61 2.6 52.4 1.0 CE1 A:HIS65 3.3 43.1 1.0 CA A:CYS61 3.4 29.5 1.0 O A:HOH465 3.5 38.2 1.0 O A:HOH328 3.6 32.2 1.0 ND1 A:HIS65 3.7 38.5 1.0 C A:CYS61 3.9 27.1 1.0 O A:CYS61 3.9 23.3 1.0 O A:HOH308 4.4 44.1 1.0 NE2 A:HIS65 4.4 37.4 1.0 O A:HOH365 4.4 41.5 1.0 N A:CYS61 4.7 24.2 1.0 O A:HOH456 4.7 29.3 1.0 OE1 A:GLU140 4.7 54.8 1.0 N A:CYS62 4.8 21.2 1.0 O A:HOH434 4.8 47.6 1.0 O A:HOH395 4.9 24.3 1.0

J.Zang, B.Zheng, X.Zhang, P.Arosio, G.Zhao. Design and Site-Directed Compartmentalization of Gold Nanoclusters Within the Intrasubunit Interfaces of Ferritin Nanocage. J Nanobiotechnology V. 17 79 2019.
ISSN: ISSN 1477-3155
PubMed: 31277668
DOI: 10.1186/S12951-019-0512-0