Gold in PDB 7x1r: Cryo-Em Structure of Human Thioredoxin Reductase Bound By Au

All present enzymatic activity of Cryo-Em Structure of Human Thioredoxin Reductase Bound By Au:
1.8.1.9;

The binding sites of Gold atom in the Cryo-Em Structure of Human Thioredoxin Reductase Bound By Au (pdb code 7x1r). This binding sites where shown within 5.0 Angstroms radius around Gold atom.
In total 2 binding sites of Gold where determined in the Cryo-Em Structure of Human Thioredoxin Reductase Bound By Au, PDB code: 7x1r:
Jump to Gold binding site number: 1; 2;

Gold binding site 1 out of 2 in the Cryo-Em Structure of Human Thioredoxin Reductase Bound By Au


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 1 of Cryo-Em Structure of Human Thioredoxin Reductase Bound By Au within 5.0Å range: probe atom residue distance (Å) B Occ A:Au502 b:36.3 occ:0.30 SG A:CYS189 2.2 28.5 1.0 CD2 A:LEU214 3.3 24.1 1.0 CB A:CYS189 3.7 28.5 1.0 CG A:LEU214 4.0 24.1 1.0 CD1 A:LEU214 4.3 24.1 1.0 O A:HIS96 4.5 24.0 1.0 CB A:TRP98 4.5 21.6 1.0 CA A:CYS189 4.8 28.5 1.0 ND1 A:HIS96 4.9 24.0 1.0

Gold binding site 2 out of 2 in the Cryo-Em Structure of Human Thioredoxin Reductase Bound By Au


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 2 of Cryo-Em Structure of Human Thioredoxin Reductase Bound By Au within 5.0Å range: probe atom residue distance (Å) B Occ B:Au502 b:38.7 occ:0.30 SG B:CYS189 2.2 28.8 1.0 CD2 B:LEU214 3.3 24.1 1.0 CB B:CYS189 3.7 28.8 1.0 CG B:LEU214 4.0 24.1 1.0 CD1 B:LEU214 4.3 24.1 1.0 O B:HIS96 4.5 24.4 1.0 CB B:TRP98 4.5 21.9 1.0 CA B:CYS189 4.8 28.8 1.0 ND1 B:HIS96 4.9 24.4 1.0

Z.Du, Z.He, J.Fan, Y.Huo, B.He, Y.Wang, Q.Sun, W.Niu, W.Zhao, L.Zhao, P.Cao, K.Cao, D.Xia, Q.Yuan, X.J.Liang, H.Jiang, Y.Gong, X.Gao. AU4 Cluster Inhibits Human Thioredoxin Reductase Activity Via Specifically Binding of Au to CYS189 Nano Today V. 47 01686 2022.
ISSN: ESSN 1878-044X
DOI: 10.1016/J.NANTOD.2022.101686