Gold in PDB 5z91: Human Mitochondrial Ferritin Mutant Bound with Gold Ions

All present enzymatic activity of Human Mitochondrial Ferritin Mutant Bound with Gold Ions:
1.16.3.1;

The structure of Human Mitochondrial Ferritin Mutant Bound with Gold Ions, PDB code: 5z91 was solved by J.Zang, B.Zheng, G.Zhao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.52 / 3.00
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	182.094, 182.094, 182.094, 90.00, 90.00, 90.00
R / Rfree (%)	18.3 / 28.1

The structure of Human Mitochondrial Ferritin Mutant Bound with Gold Ions also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Gold atom in the Human Mitochondrial Ferritin Mutant Bound with Gold Ions (pdb code 5z91). This binding sites where shown within 5.0 Angstroms radius around Gold atom.
In total 2 binding sites of Gold where determined in the Human Mitochondrial Ferritin Mutant Bound with Gold Ions, PDB code: 5z91:
Jump to Gold binding site number: 1; 2;

Gold binding site 1 out of 2 in the Human Mitochondrial Ferritin Mutant Bound with Gold Ions


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 1 of Human Mitochondrial Ferritin Mutant Bound with Gold Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Au201 b:0.8 occ:0.44 SG A:CYS130 2.4 65.4 1.0 CB A:CYS130 3.3 54.0 1.0 O A:ASP126 3.3 59.4 1.0 CA A:PRO127 3.5 53.7 1.0 C A:ASP126 3.6 57.8 1.0 N A:PRO127 3.7 53.3 1.0 O A:ALA121 3.9 51.8 1.0 CA A:SER122 4.0 52.0 1.0 CB A:PRO127 4.2 41.4 1.0 C A:ALA121 4.3 51.8 1.0 N A:SER122 4.3 61.5 1.0 N A:ASP126 4.4 52.0 1.0 OG A:SER122 4.4 71.2 1.0 CA A:CYS130 4.5 49.3 1.0 C A:PRO127 4.5 53.4 1.0 CA A:ASP126 4.6 49.2 1.0 CD A:PRO127 4.7 54.5 1.0 CB A:SER122 4.7 51.1 1.0 N A:CYS130 4.7 50.2 1.0 O A:PRO127 4.7 52.0 1.0 O A:SER122 4.8 60.9 1.0 C A:GLY125 4.9 53.7 1.0 C A:SER122 4.9 56.1 1.0 CA A:GLY125 5.0 43.0 1.0

Gold binding site 2 out of 2 in the Human Mitochondrial Ferritin Mutant Bound with Gold Ions


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 2 of Human Mitochondrial Ferritin Mutant Bound with Gold Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Au202 b:0.5 occ:0.52 SG A:CYS102 2.6 57.0 1.0 CE1 A:HIS98 3.9 67.5 1.0 NE2 A:HIS98 4.0 60.7 1.0 NE2 A:GLN90 4.1 66.8 1.0 CB A:CYS102 4.2 48.9 1.0 CA A:CYS102 4.5 48.7 1.0 ND1 A:HIS98 4.9 74.8 1.0 N A:CYS102 4.9 45.0 1.0 CD2 A:HIS98 5.0 59.7 1.0

J.Zang, B.Zheng, X.Zhang, P.Arosio, G.Zhao. Design and Site-Directed Compartmentalization of Gold Nanoclusters Within the Intrasubunit Interfaces of Ferritin Nanocage. J Nanobiotechnology V. 17 79 2019.
ISSN: ISSN 1477-3155
PubMed: 31277668
DOI: 10.1186/S12951-019-0512-0