Gold in PDB 1e3b: Cyclophilin 3 From C.Elegans Complexed with Aup(Et)3

The structure of Cyclophilin 3 From C.Elegans Complexed with Aup(Et)3, PDB code: 1e3b was solved by J.Zou, P.Taylor, J.Dornan, S.P.Robinson, M.D.Walkinshaw, P.J.Sadler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.00 / 1.85
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	61.157, 61.157, 123.077, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / 24.7

The binding sites of Gold atom in the Cyclophilin 3 From C.Elegans Complexed with Aup(Et)3 (pdb code 1e3b). This binding sites where shown within 5.0 Angstroms radius around Gold atom.
In total only one binding site of Gold was determined in the Cyclophilin 3 From C.Elegans Complexed with Aup(Et)3, PDB code: 1e3b:

Gold binding site 1 out of 1 in the Cyclophilin 3 From C.Elegans Complexed with Aup(Et)3


Mono view


Stereo pair view

A full contact list of Gold with other atoms in the Au binding site number 1 of Cyclophilin 3 From C.Elegans Complexed with Aup(Et)3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Au201 b:43.8 occ:1.00 NE2 A:HIS133 2.1 13.9 1.0 P1 A:3EP202 2.3 79.5 1.0 CD2 A:HIS133 2.8 10.3 1.0 O A:HOH2149 3.0 32.1 1.0 CE1 A:HIS133 3.2 23.5 1.0 C3 A:3EP202 3.4 0.6 1.0 CD2 A:LEU129 3.4 25.0 1.0 C5 A:3EP202 3.4 46.7 1.0 C1 A:3EP202 3.4 69.0 1.0 C2 A:3EP202 3.5 68.0 1.0 CG A:HIS133 4.0 16.5 1.0 CB A:LYS132 4.1 33.5 1.0 ND1 A:HIS133 4.2 18.6 1.0 C6 A:3EP202 4.2 54.6 1.0 C4 A:3EP202 4.5 0.7 1.0 CG A:LEU129 4.7 24.3 1.0 CG A:LYS132 4.9 43.9 1.0 CB A:LEU129 5.0 25.5 1.0 O A:LYS132 5.0 21.2 1.0

J.Zou, P.Taylor, J.Dornan, S.P.Robinson, M.D.Walkinshaw, P.J.Sadler. First Crystal Structure of A Medicinally Relevant Gold Protein Complex:Unexpected Binding of [Au(Pet (3))](+) to Histidine Angew.Chem.Int.Ed.Engl. V. 39 2931 2000.
ISSN: ISSN 1433-7851
PubMed: 11028014
DOI: 10.1002/1521-3773(20000818)39:16<2931::AID-ANIE2931>3.0.CO;2-W